Skip to main content

Osteomyelitis acuta - Streptococcus pyogenes (groep A streptokokken/GAS)

Advices

≥ 18 years
Priority Medication Remarks
Priority:
1st choice
Medication:

benzylpenicilline iv loading dose 2million. IU, 12million. IU continuous per 24 hours

followed by

clindamycine po 600mg 3dd

Priority:
2nd choice
Medication:

benzylpenicilline iv loading dose 2million. IU, 12million. IU continuous per 24 hours

followed by

amoxicilline po 750mg 3dd

≥ 18 years

Indications: Bij penicilline allergie

Priority Medication Remarks
Priority:
1st choice
Medication:

clindamycine iv 600mg 3dd

followed by

clindamycine po 600mg 3dd

Priority:
2nd choice
Medication:

cefazoline iv loading dose 1000mg, 4000mg continuous per 24 hours

followed by

clindamycine po 600mg 3dd

General comments

Zo mogelijk is chirurgisch debridement onderdeel van de behandeling. 

Na 1 week evaluatie van iv behandeling met arts-microbioloog en/of internist-infectioloog om eventueel te switchen naar oraal regime.   

Totale behandelduur: 6 weken.

Sources

Antimicrobial resources

The following antimicrobial agents have been used in these recommendations:

External antimicrobial resources
Menu position
Metadata

Swab vid: G-499262.2
Updated: 08/18/2020 - 15:41
Status: Published